Key Partner Resources: Syft Technologies Resource Centre – SIFT-MS


13th January 2022

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Here at Anatune, we regularly publish Application Notes detailing our latest innovations, methods and analytical solutions. We are also lucky to be partners with instrument manufacturers who also offer a wealth of valuable scientific content. In this edition of Key Partner Resources, we explore the Syft technologies Resource Centre and delve into the content surrounding Selected Ion Flow Tube Mass Spectrometry – SIFT-MS and real-time Mass Spectrometry analysis.

SIFT-MS is a robust analytical technique that addresses the limitations of GC/ MS.  Research has shown the benefits of SIFT-MS for real-time mass spectrometry analysis in a wide variety of applications: e.g. environmental monitoring, metabolomics, petroleum, food safety analysis, and fragrance profiling.

SIFT-MS quantifies VOCs and SVOCs in real time, with low part-per-trillion detection limits (by volume; pptv), and very wide linear and dynamic ranges. Syft Technologies’ instruments also deliver benefits in ease of use, ease of integration with other devices, remote operation and long-term calibration stability.

The merits of SIFT-MS as a separation science are clear, and the resources below offer detailed insight into how it benefits laboratory workflows, research timelines and analytical results.


SIFT-MS Resources available from Syft Technologies


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Syft Technologies Application Notes:


High-Throughput Analysis of Volatiles from Fruit Using SIFT-MS:

This application note demonstrates the simplicity with which small molecules are detected from fruits using direct SIFT-MS analysis, in contrast to conventional gas chromatographic methods. Automated SIFT-MS also provides significant throughput and method development advantages compared to conventional analytical approaches.


Real-Time, Broad-Spectrum Odor Analysis, Using SIFT-MS:

The sensitive, selective, and real-time analysis characteristic of the SIFT-MS technique provides simple, robust, and continuous analysis of extremely diverse odor compounds at trace levels in air. This application note illustrates instantaneous, broad-spectrum odor analysis with monitoring data from a chicken meat production facility.


Rapid Analysis of BTEX Using Thermal Desorption-SIFT-MS:

Selected Ion Flow Tube Mass Spectrometry – SIFT-MS – combined with GERSTEL automation greatly simplifies analysis of benzene, toluene, ethylbenzene and the xylenes (BTEX) sampled from ambient air using thermal desorption tubes. This application note demonstrates the repeatability and sensitivity achievable with automated thermal desorption (TD)-SIFT-MS. Automated TD-SIFT-MS provides sample throughputs at least three-fold higher than conventional TD-gas chromatography methods.


DOWNLOAD ALL Syft Technologies Application Notes HERE


SIFT MS Headspace


Syft Technologies Literature & Brochures:


Food, Flavour, & Fragrance Solutions Using SIFT-MS:

Flavours and aromas are primarily derived from volatile organic compounds (VOCs). VOCs are chemically very diverse, impart a wide range of favourable and unfavourable sensations to the human nose, and have a wide range of sensory thresholds. Therefore, for effective instrumental analysis a combination of characteristics is required and Selected Ion Flow Tube Mass Spectrometry (SIFT-MS) provides a unique solution to these requirements, analysing air directly and without need for sample modification. This brochure outlines several SIFT-MS- based food, flavour and fragrance solutions that Syft provides.


Environmental Solutions Using SIFT-MS:

Volatile organic compounds (VOCs) and inorganic gases are important – but usually invisible – air pollutants. Selected Ion Flow Tube Mass Spectrometry (SIFT-MS) has a unique combination of features that allow it to quantify VOCs in real time, with very high selectivity, at the required ambient concentrations, and with wide linear and dynamic ranges. SIFT-MS also delivers benefits in ease of use, ease of integration, remote operation, and long-term calibration stability. SIFT-MS presents a breakthrough in the comprehensive detection, quantification, and tracing of VOC and inorganic gas hazards and nuisances. This brochure outlines several SIFT-MS based environmental solutions provided by Syft Technologies.


SIFT-MS Solutions for Research:

Volatile and semivolatile organic compounds (VOCs and SVOCs) are ubiquitous and important in matrices as diverse as human breath, food, industry, and the atmosphere.  Gas Chromatography Mass Spectrometry (GC/MS) and High-Performance Liquid Chromatography (HPLC) are employed most commonly for VOC and SVOC analysis, but long analysis time and discrimination against certain types of compounds means that they are less appropriate for dynamic systems or high sample throughput. SIFT-MS is a robust analytical technique that addresses these limitations by quantifying VOCs and SVOCs in real time, with low part-per-trillion detection limits, and very wide linear and dynamic ranges. Syft Technologies’ instruments also deliver benefits in ease of use, ease of integration with other devices, remote operation and calibration stability. This brochure outlines the benefits that Syft Technologies’ instruments can provide to researchers in a range of disciplines.


DOWNLOAD ALL Syft Technologies Literature & Brochures HERE



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Syft Technologies Webinars:


  • Syft App Talks #23. Real-Time Acrylamide Monitoring in Food Processing Using SIFT-MS

  • Syft App Talks #22. Closed System Transfer Devices – Performance Testing Using SIFT-MS

  • Spatial and Temporal Mapping of Environmental Volatile Pollutants: Mobile SIFT-MS


Listen to all Syft Technologies’ Webinars HERE


Anatune SIFT-MS Application Notes


AS251: Real-Time Analysis of VOC Production From An Algae Bioreactor Using Select Ion Flow Tube Mass Spectrometry (SIFT-MS)

Algae can be cultivated in large bioreactors, using a range of technologies, for purposes as diverse as biomass production, water treatment and CO2 fixation. Algae biomass can be extracted or refined to produce compounds such as bioethanol or higher value products such as fatty acids and protein. The ability of Select Ion Flow Tube Mass Spectrometry – SIFT-MS – to measure gas phase volatile organic compounds (VOCs), in real-time, offers a unique approach to monitoring critical compounds produced by the bioreactor, potentially at low parts-per-billion by volume (ppbV) levels. This Application Note demonstrates the ability of SIFT-MS and shows the utility of this approach in maximising outcomes.


AS245: The Use of SIFT-MS in the Assessment of Food Quality – Smoked Salmon

The measurement of volatile compounds in food can be critical in understanding the flavour profile of a product and ensuring the quality and authenticity for the consumer. The complexity of the matrix can sometimes present a challenge and can often require considerable sample preparation protocols to enable detection of analytes at low levels. Selected Ion Flow Tube Mass Spectrometry (SIFT-MS) is a real-time volatile organic compounds (VOC) analyser. This application note demonstrates SIFT-MS food analysis, using SIFT-MS to compare the volatile profiles of smoked salmon samples and illustrates the potential of this approach for both targeted and untargeted analysis.


AS244: Methanolic Extraction of Soils by Automated Selected Ion Flow Tube Mass Spectrometry (SIFT-MS)

Soil can become contaminated with benzene, toluene, xylenes and ethylbenzene (BTEX) from a number of source and may pose health and ecological risks. Automated SIFT-MS is a powerful technique for the analysis of volatiles, from a range of different matrices, and benefits from significant throughput gains, versus more conventional chromatographic techniques. Methanolic extraction followed by GC-MS analysis is a common method for determination of BTEX in soil and this Application Note demonstrates that GC-MS methods, even those with more complex sample preparation requirements, can readily be converted to automated SIFT-MS methods, with all the throughput gains and ease of analysis that this brings.


AS241: Monitoring Acrylamide in Real-Time During Food Production Using SIFT-MS

Real-Time VOC Analysis: Food production processes, particularly those that involve heating are responsible for the formation of volatile organic compounds (VOCs), some of which may be important for the flavour of the finished product, whilst others can be considered contaminants and may be of toxicological concern. Selected Ion Flow Tube Mass Spectrometry (SIFT-MS) is a real-time volatile organic compounds (VOC) analyser, enabling real-time VOC analysis and monitoring of acrylamide throughout the production process. This study demonstrates the use of SIFT-MS to for real-time VOC analysis of volatile compounds such as acrylamide, that are formed during certain food production processes.


DOWNLOAD ALL Anatune SIFT-MS Application Notes HERE

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