Use of SPE and Twister (SBSE) to Enrich Heptachlor and Heptachlor Epoxide From Water with a GC/Q-TOF in NCI

Martin Perkins

2nd June 2017

A previous application note (AS168) has been written which shows the determination of Organochlorine pesticides (OCPs) in water down to ppt (ng/l) levels using a GC/Q-TOF.

From the OCPs, Heptachlor and Heptachlor Epoxide were chosen to develop an enrichment method using Solid Phase Extraction followed by Twister™ to determine even lower detection limits down to ppt levels. Twister extraction is also known in literature as Stir Bar Sorptive Extraction (SBSE).