AS172: A Fully Automated On-line Forensic Toxicology Solution for the Determination of Opioids in Blood by Smart SPE Clean-Up and GC-MS

Anatune

21st July 2021


A Fully Automated On-line Forensic Toxicology Solution for the Determination of Opioids in Blood by Smart SPE Clean-Up and GC-MS

Many forensic toxicology service labs are facing increasing casework, often times with reduced staff numbers. While there is significant pressure on the lab analysts to reduce case turnaround times (TATs), it is essential that the results are reproducible and reliable for consideration as evidence in a Court of Law.

Automation of the sample preparation workflow can not only offer faster TATs and excellent repeatability of results, but it can also free up the lab analysts for thinking tasks such as data analysis, method development and reporting.

This application note describes the fully automated on-line Forensic Toxicology Solution for the determination of four forensically-relevant opiates in blood by gas chromatography-mass spectrometry (GC-MS), including morphine, 6- monoacetylmorphine (6-MAM), codeine and dihydrocodeine (DHC).

 

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